How Hydroxychloroquine Make You Gain Weight


hydroxychloroquine make you gain weight for various medical conditions. This is a prescription medication used to treat a variety of conditions, including malaria, rheumatoid arthritis, and lupus. It is generally considered to be a safe and effective drug, but it can have some side effects.

Weight gain is not a known side effect of this medicine. In fact, in some other studies, we have also seen that HC may actually help in weight loss in some cases.

Here we will discuss briefly about hydroxychloroquine make you gain weight. And will also discuss other possible causes of weight gain and how to lose weight safely.

What is Hydroxychloroquine?

This is a Medicine used to treat a variety of conditions, including:

  • Malaria
  • Rheumatoid arthritis
  • Lupus
  • Porphyria cutanea tarda
  • Discoid lupus erythematosus
  • Subacute cutaneous lupus erythematosus

HC is an antimalarial drug that works by killing the malaria parasite. It is also an immunosuppressant, which means that it suppresses the immune system. This is why it is used to treat autoimmune diseases like rheumatoid arthritis and lupus.

How Does Hydroxychloroquine Work?

This works in a number of ways, depending on the condition it is being used to treat. As for Malaria, HC kills that parasite by interfering with its ability to produce energy. In rheumatoid arthritis and lupus, it reduces inflammation by suppressing the immune system. In porphyria cutanea tarda case HC reduces the production of porphyrins, which are chemicals that can build up in the skin and cause damage. This also reduces inflammation and helps to prevent new skin lesions from forming.

Hydroxychloroquine Make You Gain Weight

 Gaining weight is not a known side effect In fact, some studies have shown that HC may actually help with weight loss. One study, published in the journal Obesity, found that people with lupus who were taking this lost an average of 1.5% of their body weight over 12 months. Another study, published in the journal Arthritis & Rheumatism, found that people with rheumatoid arthritis who were taking HC lost an average of 2.5% of their body weight over 12 months.

Hydroxychloroquine make you gain weight However, other studies have found no link between HC and weight loss. For example, a study published in the journal PLoS One found that people with malaria who were taking HQ did not lose any weight over 14 days.

hydroxychloroquine make you gain weight

Why Might Hydroxychloroquine Help With Weight Loss?

There are a few possible reasons why this medication might help with weight loss.

Reduced inflammation:

Inflammation is a process that the body uses to fight off infection and injury. However, chronic inflammation can lead to a number of health problems, including weight gain. This medicine may help to reduce inflammation by suppressing the immune system.

Reduced appetite:

Appetite is regulated by a number of factors, including hormones and hormones and this chemical may help to reduce appetite by affecting the levels of certain hormones.

Increased metabolism:

Metabolism is the process by which the body converts food into energy. Medicine may help to increase metabolism by increasing the activity of the thyroid gland.

How to Lose Weight Safely

Because we know that hydroxychloroquine make you gain weight but your doctor can help you to determine the cause of your weight gain and develop a plan to lose weight safely.

You can follow these tips for safely losing weight:

  • Take less sugary drinks and unhealthy fats.
  • You can create a calorie deficit by eating less, exercising more, or doing both.
  • Be patient and follow your diet because Losing weight takes time and effort.

The Mechanism of Weight Gain

The precise mechanism underlying the hydroxychloroquine make you gain weight remains a subject of ongoing investigation. It is postulated that the medication may influence factors related to appetite regulation or metabolism. Moreover, in individuals utilizing this chemical to manage autoimmune conditions, the relief of symptoms, reduced inflammation, and improved overall well-being may indirectly contribute to a healthier appetite and potential weight gain.

Clinical Studies and Empirical Evidence

Research on the connection between hydroxychloroquine make you gain weight is nuanced and not universally conclusive. While some studies have reported weight gain as a potential side effect, others have failed to establish a significant correlation. It is essential to recognize that individual responses to medications can vary, and variables such as dosage, duration of use, and pre-existing health conditions may influence outcomes.

Balancing Benefits and Potential Risks

For individuals prescribed about hydroxychloroquine make you gain weight, it is crucial to carefully weigh the potential benefits of the medication against any potential side effects, including the possibility of weight gain. Doctors adopt a vigilant approach, monitoring patients closely and, when necessary, adjusting dosages or considering alternative treatments to optimize therapeutic efficacy while prioritizing overall well-being.

Holistic Approaches to Health

Irrespective of medication use, a holistic approach to health is paramount. This encompasses maintaining a balanced diet, engaging in regular exercise, managing stress, and prioritizing mental well-being. For individuals concerned about weight gain while using hydroxychloroquine, adopting a comprehensive approach to health can be particularly beneficial.


As we know that hydroxychloroquine make you gain weight but there is no such known side effect of this medicine. But If you are taking it and you are experiencing weight gain, it is important to talk to your doctor. There may be another underlying cause of your weight gain, such as a change in your diet or exercise habits.

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